All functions

BST1

echolocatoR output example: BST1 locus

BST1_LD_matrix

LD with the lead SNP: BST1 locus

LRRK2

echolocatoR output example: LRRK2 locus

MEX3C

echolocatoR output example: MEX3C locus

R.utils

R.utils

assign_lead_snp()

Assign lead SNP

column_dictionary()

Map column names to positions.

construct_colmap()

Target column map

coords_to_rsids()

Get RSIDS from SNP coordinates

createDT()

Interactive DT

detect_genes()

Detect QTL genes in full summary stats file

dt_to_granges()

Convert data.table to GRanges object

example_fullSS()

Store fullSS_dat

extract_loci()

Extract loci from GWAS/QTL summary statistics

fillNA_CS_PP()

Fill NAs in PP and CS columns

filter_snps()

Filter SNPs

find_consensus_snps()

Find Consensus SNPs

find_consensus_snps_no_polyfun()

Find Consensus SNPs: without PolyFun

find_top_consensus()

Find the top Consensus SNP

fix_coltypes()

Automatically fix column types

gene_locus_list()

Generate a named list of (e)Gene-Locus pairs

genome_wide_dir

Example results path for genome-wide results

get_CS_bins()

Get Credible Set bins

get_CS_counts()

Get Credible Set SNP counts

get_Kunkle2019()

Example GWAS summary statistics: Kunkle2019

get_Kunkle2019_coloc()

Get colocalization results with Kunkle2019 GWAS

get_Nalls2019()

Example GWAS summary statistics: Nalls2019

get_Nalls2019_coloc()

Get colocalization results with Nalls2019 GWAS

get_Nalls2019_loci()

echolocatoR output example: select loci

get_Nalls2019_merged()

echolocatoR output example: all loci

get_SNPgroup_counts()

Get SNP group counts

get_data()

Get data

get_header()

Get file header

get_nrows()

Get nrows

get_os()

Get OS

get_sample_size()

Get sample size

granges_to_bed()

Convert from GRanges to BED format

import_topSNPs()

Import top GWAS/QTL summary statistics

is_empty()

Check if a file is empty

is_ggbio()

Is an object of class ggbio

is_ggplot()

Is an object of class ggplot

is_granges()

Is an object of class GRanges

is_local()

Is local

is_url()

Check if the input is url e.g. http:// or ftp://

limit_snps()

Limit the number of SNPs per locus.

locus_dir

Example results path for Nall2019 BST1 locus

melt_finemapping_results()

Melt fine-mapping results

merge_finemapping_results()

Merge fine-mapping results from all loci

merge_robust()

Merge robust

mungesumstats_to_echolocatoR()

Convert from MungeSumstats to echolocatoR format

order_loci()

Order loci

portal_metadata()

Import metadata

portal_query()

Search and download fine-mapping files

preview()

Preview formatted sum stats saved to disk

read_parquet()

Read parquet file

reassign_lead_snps()

Reassign lead SNPs

results_report()

Results report

set_permissions()

Set permissions

snp_group_colorDict()

Assign colors to each SNP group

snp_group_filters()

Get SNP group filters

standardize()

Standardize the locus subset

standardize_gene()

Standardize genes

sumstatsColHeaders

sumstatsColHeaders from MungeSumstats

topSNPs_Kunkle2019

TopSS example file (processed): Kunkle2019

topSNPs_Nalls2019

TopSS example file (processed): Nalls2019

topSNPs_Nalls2019_raw

TopSS example file: Nalls2019

unlist_dt()

Unlist a data.table

update_cols()

Update CS cols

write_parquet()

Write parquet file